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Generic Name: isradipine (is RA di peen)
Brand Names: Dynacirc, Dynacirc CR

What is Dynacirc CR (isradipine)?

Isradipine is in a class of drugs called calcium channel blockers. Isradipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for your heart to pump and reduces its workload.

Isradipine is used to treat hypertension (high blood pressure).

Isradipine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Dynacirc CR (isradipine)?

What should I discuss with my healthcare provider before taking Dynacirc CR (isradipine)?

Before taking this medication, tell your doctor if you have

• kidney disease;

• liver disease;

• other diseases of the heart or blood vessels such as congestive heart failure, low blood pressure, or coronary artery disease; or

• a condition involving narrowing of your esophagus, stomach, or intestinal tract.

You may not be able to take isradipine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

How should I take Dynacirc CR (isradipine)?

Take isradipine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Symptoms of an isradipine overdose include dizziness, weakness, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.

What should I avoid while taking Dynacirc CR (isradipine)?

Dynacirc CR (isradipine) side effects

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• an unusually fast or slow heartbeat;

• fainting or severe dizziness;

• abnormal behavior or psychosis;

• chest pain;

• jaundice (yellowing of your skin or eyes); or

• swelling of your legs or ankles.

Other less serious side effects may be more likely to occur. Continue to take isradipine and talk to your doctor if you experience

• unusual headache, fatigue, or tiredness;

• mild dizziness;

• nausea, vomiting, or diarrhea;

• flushing; or

• a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Dynacirc CR (isradipine)?

Tell your doctor if you are taking any other heart medicines. Isradipine and other heart medicines may have additive effects.

Drugs other than those listed here may also interact with isradipine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about isradipine written for health professionals that you may read.

What does my medication look like?

Isradipine is available with a prescription under the brand name Dynacirc. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Dynacirc 2.5 mg--white capsules

• Dynacirc 5 mg--light-pink capsules

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.